© International Commission on Radiation Units and Measurements 2008
4. General Aspects of Dosimetry for Radiation Processing
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Accurate dose measurements, traceable to recognized national standards, are an essential component of industrial radiation processing. Applications such as the sterilization of medical devices and the irradiation of foodstuffs are both highly regulated and international in nature. In order to ensure both the safety of the process and to facilitate international trade, it is essential that a widely accepted system of calibration and traceability be in place. Mutual equivalence and recognition of high-dose dosimetry standards are achieved both by experimental comparisons and by the adoption of standard procedures and methods, including formal accreditation of calibration laboratories by independent third parties. Dose measurements in industrial irradiation plants pose particular difficulties because the behavior of many dosimetry systems is influenced by the
4.1 Primary Standards and Measurement Traceability
4.2 External Influence Quantities
4.3 Methods of Calibration
4.3.1 Calibration of Reference Standard Dosimeters
4.3.2 Calibration of Routine Dosimeters
4.3.2.1 Calibration in the Irradiation Plant
4.3.2.2 Irradiation at a Calibration Facility Followed by In-Plant Verification
4.4 Measurement Uncertainties
4.4.1 Uncertainties in the Preparation of a Calibration Function
4.4.1.1 Uncertainty in Calibration Doses
4.4.1.2 Uncertainty Associated with Fitting of a Calibration Function
4.4.1.3 Uncertainty Associated with Environmental Influence Quantities
4.4.2 Uncertainties in the Use of Dosimeters
4.4.2.1 Uncertainty Associated with Dosimeter-to-Dosimeter Variation
4.4.2.2 Uncertainty Associated with Variation in Plant Environmental Condition
4.4.2.3 Uncertainty Associated with Instability of Dosimeter Signal
4.4.2.4 Uncertainty Associated with Instability and Variability of Instrumentation
4.4.3 Application of Uncertainty Data
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